Sadness and the Cell: Is Depression All in Your Body or is it All in Your Mind

Very interesting approach to depression and promising in some ways. In my opinion, a much better and already successful approach is that of William Walsh who defines five distinct depression types based on blood and urine analyses of 10,000’s of cases. People with different depression types need to be treated completely differently: some can do well on SSRI’s but one type does very badly on SSRI’s, including potentially violently behavior, but all types respond well to nutritional treatment. Depression types identified by Dr Walsh can be caused by toxins such as mercury and lead (~5% of depression cases), by severe deficiency in vitamin B6 called pyrrole disorder (~15% of depression cases), over or under methylation, or copper overload (mostly in women). I would like to see the research in this talk combined with the biochemical clinical approach used by Dr Walsh. As mentioned in this talk, inflammation can be a major factor in depression, but what is causing the inflammation? Stress (much can related to life traumas), leaky gut (see Dr Perlmutter), genetics (including mutations such as MTHFR), and of course diet and lifestyle. One of the biggest problems in psychiatry is probably that they see depression as a single illness, rather than a set of symptoms that can have many different causes as discussed by Dr Walsh.